The visitors had adapted better to the icy conditions and enjoyed the majority of the better chances in the opening 45 minutes, with Bees' keeper Paul Smith making one or two tremendous saves, before Colchester's Scott McGleish rattled a post.
Brentford had had chances of their own, most notably midfielder, Kevin O.Connor, who shot straight at the Essex side's custodian, Simon Brown, when clean through, and Stephen Hunt also wasted a gilt edged opportunity.
However, with the players continually slipping and sliding, the referee, after reviewing the state of the playing surface at half time, was left with no alternative but to abandon the contest, the first time in over 35 years that a competitive fixture has been called off at the ground.
The clash appears fated to the elements, as the original game scheduled to take place on New Years Day was postponed due to a waterlogged pitch.
No new date has as yet been announced for the fixture.