Brentford bowed out of the Worthington Cup when they lost 4-1 at Griffin Park against a Middlesbrough side that made 11 changes from the team that beat Spurs at the weekend.
Boro opened well and Bees keeper Paul Smith made two good saves in the opening couple of minutes. He tipped over a 25-yard Noel Whelan volley and seconds later made a good save from Luke Wilkshire.
After 15 minutes a Michael Dobson cross from the right found Mark McCammon and his header was saved easily by keeper Mark Crossley.
The first of three Brentford bookings came a minute later when Jamie Fullerton was yellow carded for a foul.
Boro opened the scoring in the 18th minute when Allan Johnston's low cross from the left found Carlos Marinelli in the box and he controlled the ball before firing home a left-foot strike into the bottom right-hand corner of the net.
Two minutes later the visitors extended their lead when Marinelli held off several defenders and crossed for Whelan to tap the ball home from close range.
Two minutes later at the other end a Rowan Vine shot on the turn in the box was easily saved and in the 25th minute Vine shot on the turn but his effort flashed just wide of the right-hand post.
Seven minutes before the break Leo Roget was booked for a foul on Marinelli. Bees' man of the match Vine saw another effort well saved by Croslley at the near post just before the break.
Two minutes after half time Whelan was yellow carded for a lunge on Roget.
On the hour mark Vine had an effort well saved by Crossley and Kevin O'Connor saw his shot again saved by the keeper.
The Bees' third and final booking came in the 72nd minute when Vine was yellow carded for a foul on Colin Cooper.
Just 15 minutes from time Mark Wilson fired home a left-foot effort high into the roof of the net from 20 yards to score Boro's third goal and a minute later substitute Stewart Downing fired home left footed low into the right-hand corner of the net for number four.
The Bees scored a consolation goal in the dying minutes when Ibrahima Sonko headed home from a right-wing corner.